Seroxat and Seroquel & Pregnancy
[Home] [Bipolar News] [Bipolar Disorder] [Medications] [Treatments] [Bipolar Disorder/Job/School] [Disabilities] [Ask the Doctor] [Ask David] [Self-Injury] [Personal Stories] [Graham's Column] [Steven's Column] [Storm's Column] [Columnist Archives] [Suicide] [Community Support] [Family Members] [Expressions] [Greeting Cards] [Books] [Awards] [Links & Rings] [About Us] [Contact Us]


Q:  Seroxat and Seroquel & Pregnancy

Dear Dr. Phelps

I have bi-polar disorder, and have been successfully treated with lithium (600Mg) combined with seroxat (30 mg) for the past seven years.

At the age of 35, my husband and I are keen to start a family.  I have therefore been 'weened' off Lithium and have been taking seroquel (400mg) for the past 3 months.  Please would you advise me what your thoughts on this medication and the effects which may be detrimental during the pre and post natal stage?

Being aware of the difficulties reported of multiple drugs during pregnancy, it is indeed my intention to reduce the seroxat over a sensible time period.

Your advise would be greatly apprecicated.


Dear Ms. C' -- 
This is such a controversial area, largely because we lack the most basic information about safety, I'm afraid I cannot advise or really even comment much.  There are no good answers, no way to even lay out a spectrum of options and rank them based on their respective safety levels (isn't that frustrating? on the other hand, think how long it takes to accumulate enough data to be able to do that reliably; lithium is really the only one of those you name where we know much about risk -- somewhat with the Seroxat (paroxetine; Paxil), almost nothing with the Seroquel except that theoretically it's in roughly the same family as the old-generation antipsychotics which over many, many years have appeared to be relatively safe -- at least no obvious problems as we've seen for other agents.) Sorry about that. I face the same problem counseling my own patients on their options. 

Dr. Phelps

Published September, 2005


Bipolar World   1998, 1999, 2000, 2001, 2002, 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014
Allie Bloom, David Schafer, M.Ed. (Blackdog)
Partners:  John Haeckel, Judith (Duff) 
Founder:  Colleen Sullivan

Email Us at Bipolar World


About Us  Add a Link  Advance Directives  Alternative Treatments  Ask the Doctor   Ask Dr. Plyler about Bipolar Disorder   Ask The Doctor/ Topic Archives  Awards  Benny the Bipolar Puppy  Bipolar Chat  Bipolar Children  Bipolar Disorder News  Bipolar Help Contract  Bipolar World Forums  Book Reviews  Bookstore  BP & Other mental Illness   Clinical Research Trials & FDA Drug Approval   Community Support   Contact Us  The Continuum of Mania and Depression   Coping   Criteria    Criteria and Diagnosis  Criteria-World Health Disabilities,  DSMV-IV   Dual Diagnosis  eGroups  Expressions (Poetry, Inspiration, Humor, Art Gallery, Memorials  Family Members   Getting Help for a Loved One who Refuses Treatment  Greeting Cards  History of Mental Illness  Indigo  Job and School  Links  Manage Your Medications  Medications   Medication and Weight Gain    News of the Day  Parent Chat  Pay for Meds  Personal Stories  Self Help  Self Injury  Significant Others  Stigma and Mental Health Law  Storm's Column  Suicide!!!  The Suicide Wall  Table of Contents   Treatments  Treatment Compliance  US Disability  Veteran's Chat  What's New?