Is Zyprexa a Long-term Treatment for Me?
[Home] [Bipolar News] [Bipolar Disorder] [Medications] [Treatments] [Bipolar Disorder/Job/School] [Disabilities] [Ask the Doctor] [Ask David] [Self-Injury] [Personal Stories] [Graham's Column] [Steven's Column] [Storm's Column] [Columnist Archives] [Suicide] [Community Support] [Family Members] [Expressions] [Greeting Cards] [Books] [Awards] [Links & Rings] [About Us] [Contact Us]

 


Q:  Is Zyprexa a Long-term Treatment for Me?


Dr. Phelps

I have BP II. My medications are: Lamictal - 300 mg, Zyprexa - 7.5 mg, Wellbutrin - 200 mg, and .5 mg Klonopin as needed.  Doctor agreed to taper down Zyprexa as it was not thought to be a long-term med in the plan - was placed in plan after hypomanic after SSRI Celexa (subscribed by psychiatric nurse practioner who did not believe I have BP).  I really wanted the change as I have gained 50 lbs while on Zypexa.  Dr. instructed that I was to taper Zyprexa to .5 mg for one month, and 2.5 mg the following month.  Had a slight hypomania followed by a crash into depression while on .5 mg.  Just after starting the 2.5 mg taper realized that something was wrong (suicide thoughts, severe anxiety, missing work, etc.)

Immediately went to see my Dr. She returned me to the 7.5 mg dose of Zyprexa.  The improvement in my depression was almost  unbelievable.  Took the Zyprexa before bed and woke up fealing 100% better.

My question:  is Zyprexa a long-term treatment for BP II and would you consider continuing it long-term based on what I have written?

Thanks -- Ask the Doctor is a real blessing to me.
 

Dear Terry -- 
Because Wellbutrin is still in there, an antidepressant, I think it may take a while to determine whether lamictal alone might hold your symptoms under control. You'd have to taper the Wellbutrin very slowly, just as you were doing with the Zyprexa, and then try tapering the Zyprexa again -- this time without Wellbutrin around. The hope would be that Wellbutrin may have made you "need" Zyprexa by contributing to the potential for manic-side symptoms (just as Celexa did), and that without it, perhaps you wouldn't "need" the Zyprexa anymore. That's all theory of course but needs to be considered before you conclude you're "stuck" on Zyprexa. If you were indeed "stuck" that way, check out the teeny smidgin of information on Zyprexa Zydis allowing those who've gained on Zyprexa to turn around and lose it while still on Zyprexa (huh?
check it out). 

Of course all of this theory must be discussed with your doctor for her impressions and so that the two of you can make a plan together. Good luck with that. 

Dr. Phelps 



Published August, 2005
 

 

Bipolar World   1998, 1999, 2000, 2001, 2002, 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014
Owners: 
Allie Bloom, David Schafer, M.Ed. (Blackdog)
Partners:  John Haeckel, Judith (Duff) 
Founder:  Colleen Sullivan
 

Email Us at Bipolar World

 

About Us  Add a Link  Advance Directives  Alternative Treatments  Ask the Doctor   Ask Dr. Plyler about Bipolar Disorder   Ask The Doctor/ Topic Archives  Awards  Benny the Bipolar Puppy  Bipolar Chat  Bipolar Children  Bipolar Disorder News  Bipolar Help Contract  Bipolar World Forums  Book Reviews  Bookstore  BP & Other mental Illness   Clinical Research Trials & FDA Drug Approval   Community Support   Contact Us  The Continuum of Mania and Depression   Coping   Criteria    Criteria and Diagnosis  Criteria-World Health Disabilities,  DSMV-IV   Dual Diagnosis  eGroups  Expressions (Poetry, Inspiration, Humor, Art Gallery, Memorials  Family Members   Getting Help for a Loved One who Refuses Treatment  Greeting Cards  History of Mental Illness  Indigo  Job and School  Links  Manage Your Medications  Medications   Medication and Weight Gain    News of the Day  Parent Chat  Pay for Meds  Personal Stories  Self Help  Self Injury  Significant Others  Stigma and Mental Health Law  Storm's Column  Suicide!!!  The Suicide Wall  Table of Contents   Treatments  Treatment Compliance  US Disability  Veteran's Chat  What's New?