Risperdal & Confused Thinking from Topomax
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Q:  Risperdal & Confused Thinking from Topomax

I am currently taking Zoloft, Lamictal, and Risperdal for bipolar II and doing quite well, except for a lot of weight gain.  While taking Zoloft and Topamax a year ago (without Risperdal), I lost  weight but became increasingly confused.  My question is, if I switch from Lamictal back to Topamax, will the Risperdal I'm now taking counteract the confused thinking caused by the Topamax? 

Thank you.

Dear Ms. G' -- 
Nice thought, but nope.  Actually, I suppose I should see someone try it before being so certain-sounding.  But the confused thinking caused by Topomax is similar to that we see with other anticonvulsants when they're combined with other medications:  slowed, disorganized, memory impairment.  Risperidone is not designed to affect this kind of thing.  So on solid theoretical grounds, I would predict -- that's a better way of putting it -- that this wouldn't work and I wouldn't be walking around with much doubt in my mind about it!  

Dr. Phelps

Published March, 2003


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