Depakote ER
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Q:  Depakote ER


My doctor had to take me off Trileptal because of a sodium problem. The medicine was working very well. I've been switched to Depakote ER. What have been your experiences with the new form of Depakote? The older kind had much worse side effects for me.


Dear Ms. S' -- 
I've been quite impressed with the new form as able to keep people from getting side effects they might have gotten on the older version.  E.g. people can take 1000mg ER and much less commonly see the appetite that leads to weight gain; and many more people can get to 1500mg ER without that appetite thing (where with the older version, it seemed to me that few people, and few women especially, could get to 1500 or even 1250 (which is a truer comparison for the ER version in that at about 80-85% absorption for the ER version that comes to about 1300 mg total)). 

Dr. Phelps

 

Published May, 2002 

 

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