Meds & False Negative Pregnancy Test
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Q:  Meds & False Negative Pregnancy Test

Dear Dr. Phelps:
I am bipolar and am taking effexor, depokote, clonopin, and trazadone. I have missed 2 menstrual cycles and have many signs of pregancy, but the blood tests for pregnancy are coming back negative. I haven't felt this way since my last pregancy, which was before I was on any medication. My question is: Can these medications give a false negative on the blood test for pregnancy? Thank you for your time, Jill

Dear Jill  -
Haven't ever heard of a false negative induced by these medications.  However, feeling like there's been some huge hormonal change, and missing periods, could be related.  There's a lot of concern about Depakote causing something called
polycystic ovarian syndrome, which could be associated with missed periods and feeling different (although it may be that it's the thing we're treating with Depakote, not the Depakote itself, that causes PCOS; or that both are true). 

Dr. Phelps

Published May, 2002 


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