Worse on Wellbutrin
[Home] [Bipolar News] [Bipolar Disorder] [Medications] [Treatments] [Bipolar Disorder/Job/School] [Disabilities] [Ask the Doctor] [Ask David] [Self-Injury] [Personal Stories] [Graham's Column] [Steven's Column] [Storm's Column] [Columnist Archives] [Suicide] [Community Support] [Family Members] [Expressions] [Greeting Cards] [Books] [Awards] [Links & Rings] [About Us] [Contact Us]

 


Q:  Worse on Wellbutrin


I have been on Trileptal since August.  The side effect profile is excellent and it seemed to have a calming affect. This fall I got very depressed again. AFter going up on my Trileptal my pdoc and I decided to cautiously add Wellbutrin since I"ve had bad affects from the SSRI meds.  I did very well the first two weeks. It calmed me down.But now I'm more depressed and have extreme dark moods with suicidal thoughts. They change very rapidily. What is going on?  I'm afraid to tell my doctor. I don't want to get put away.  I want to find an antidepressent that works.  

Sharon


Dear Sharon -- 
That could have been the very thing that makes me so reluctant to use antidepressants in anybody with bipolar disorder: they make the depression better but the make the "big picture" worse: in not too long, you begin to see "rapid cycling" and "mixed states".  Your "extreme dark moods and suicidal thoughts" could be that.  

Of course I can't make a certain diagnosis here on this much info'.  You should definitely tell your doc' and look for another way to address the depression.  Usually when this kind of thing happens, in retrospect we can see that the depression was not "pure", but had mixed state elements: insomnia, irritability, agitation, difficulty concentrating.  If that's the case, I avoid antidepressants and look for more mood stablilizer -- either increasing one or adding another.  Check out some recent experience with thyroid hormone for that role.  

In any case, do tell your doctor, as you'll need to change what you're doing (as you've already figured out...).  I hope you find something more satisfactory soon.

Dr. Phelps

Published November, 2001

 

Bipolar World   1998, 1999, 2000, 2001, 2002, 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014
Owners: 
Allie Bloom, David Schafer, M.Ed. (Blackdog)
Partners:  John Haeckel, Judith (Duff) 
Founder:  Colleen Sullivan
 

Email Us at Bipolar World

 

About Us  Add a Link  Advance Directives  Alternative Treatments  Ask the Doctor   Ask Dr. Plyler about Bipolar Disorder   Ask The Doctor/ Topic Archives  Awards  Benny the Bipolar Puppy  Bipolar Chat  Bipolar Children  Bipolar Disorder News  Bipolar Help Contract  Bipolar World Forums  Book Reviews  Bookstore  BP & Other mental Illness   Clinical Research Trials & FDA Drug Approval   Community Support   Contact Us  The Continuum of Mania and Depression   Coping   Criteria    Criteria and Diagnosis  Criteria-World Health Disabilities,  DSMV-IV   Dual Diagnosis  eGroups  Expressions (Poetry, Inspiration, Humor, Art Gallery, Memorials  Family Members   Getting Help for a Loved One who Refuses Treatment  Greeting Cards  History of Mental Illness  Indigo  Job and School  Links  Manage Your Medications  Medications   Medication and Weight Gain    News of the Day  Parent Chat  Pay for Meds  Personal Stories  Self Help  Self Injury  Significant Others  Stigma and Mental Health Law  Storm's Column  Suicide!!!  The Suicide Wall  Table of Contents   Treatments  Treatment Compliance  US Disability  Veteran's Chat  What's New?