Lamotrigine Appropriate Substitute?
[Home] [Bipolar News] [Bipolar Disorder] [Medications] [Treatments] [Bipolar Disorder/Job/School] [Disabilities] [Ask the Doctor] [Ask David] [Self-Injury] [Personal Stories] [Graham's Column] [Steven's Column] [Storm's Column] [Columnist Archives] [Suicide] [Community Support] [Family Members] [Expressions] [Greeting Cards] [Books] [Awards] [Links & Rings] [About Us] [Contact Us]


Q:  Lamotrigine Appropriate Substitute?

treatment for acute hypomania secondary to very severe head injury: 200mg lithium and 1200mg valproate. pretty much stable yet experiencing large amounts of pain and stiffness in injured hip and leg which i beleive to be the valproate. tried reducing dose but anxiety increases and cannot sleep etc. taken strong painkillers but only excerberate anxiety and result in taking higher doses of valproate.

tried lith, valp, and carb and combos and present combo seems to be best.  but this weakness and pain is forcing me to look elsewhere. is lamotrigine an appropriate substitute and what is the efficacy? due to head injury are the side effects that will be intollerable?

i hope to hear from you soon,

thanks, simon

Dear Simon -- 
Carb' not tolerated well?  did it give pain relief, though, as it sometimes does?  If not tolerated but otherwise maybe helpful, you could try Trileptal as a substitute with possibly less side effects (same med with an oxygen stuck on, maybe a little easier to take). 

Lamotrine would be okay to try as far as I know, check it with your doc'.  Remember, you have to be even more cautious than usual if you add it to Depakote (e.g. see my handout for patients, for review with your doc').  

Dr. Phelps

Published September, 2001


Bipolar World   1998, 1999, 2000, 2001, 2002, 2003, 2004, 2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013, 2014
Allie Bloom, David Schafer, M.Ed. (Blackdog)
Partners:  John Haeckel, Judith (Duff) 
Founder:  Colleen Sullivan

Email Us at Bipolar World


About Us  Add a Link  Advance Directives  Alternative Treatments  Ask the Doctor   Ask Dr. Plyler about Bipolar Disorder   Ask The Doctor/ Topic Archives  Awards  Benny the Bipolar Puppy  Bipolar Chat  Bipolar Children  Bipolar Disorder News  Bipolar Help Contract  Bipolar World Forums  Book Reviews  Bookstore  BP & Other mental Illness   Clinical Research Trials & FDA Drug Approval   Community Support   Contact Us  The Continuum of Mania and Depression   Coping   Criteria    Criteria and Diagnosis  Criteria-World Health Disabilities,  DSMV-IV   Dual Diagnosis  eGroups  Expressions (Poetry, Inspiration, Humor, Art Gallery, Memorials  Family Members   Getting Help for a Loved One who Refuses Treatment  Greeting Cards  History of Mental Illness  Indigo  Job and School  Links  Manage Your Medications  Medications   Medication and Weight Gain    News of the Day  Parent Chat  Pay for Meds  Personal Stories  Self Help  Self Injury  Significant Others  Stigma and Mental Health Law  Storm's Column  Suicide!!!  The Suicide Wall  Table of Contents   Treatments  Treatment Compliance  US Disability  Veteran's Chat  What's New?