Pharmacist asks Questions |
doctor, i am a pharmacist in new york state working on a project regarding bipolar disorder. two questions which have been raised which i'm having trouble answering are:which drug is less
likely to cause cognitive dulling,lithium or depakote? and long-term outcomes for patients with bipolar disorder are considered poor--true or false? thank you.
Dear NYPharm' --
2. Outcomes are extremely varied, from no recurrence of mania after one clear episode -- i.e. "full recovery", we would have to say; to steady de! clines in overall life/mood stability, and attendant loss of function, within a few years. The latter course is not common, but unfortunately not rare either. I have heard Mauricio Tohen of Harvard cite a figure of 10% for that former course of no recurrence, though (although this was his specialty at the time, these estimates) that figure is hard to imagine given my experience; on the other hand, I wouldn't see those people again to know they'd recovered, now, would I?