Antidepressants … Weight Gain and Sedation

 

The table below indicates which antidepressants are most likely to promote weight gain at the dosage ranges given.  Normally the higher the dose the more will be the likelihood of weight gain.

 

Generic Name

 

Imipramine

 

Desipramine

 

Amitriptyline

 

Nortrtriptyline

 

Protriptyline

 

Trimipramine

 

Doxepin

 

Maprotiline

 

Amoxapine

 

Trazodone

 

Fluoxetine

 

Buproprion-S.R.

 

Buproprion

 

Sertraline

 

Paroxetine

 

Venalfaxine-XR

 

Venalfaxine

 

Nefadozone

 

Fluvoxamine

 

Mirtazapine

 

 

 

MAO’s

 

Phenelzine

 

Tranylcypromine

 

Brand Name

 

Tofranil

 

Norpramin

 

Elavil

 

Aventyl

 

Vivactil

 

Surmontil

 

Sinequan

 

Ludiomil

 

Asendin

 

Desyrel

 

Prozac

 

Wellbutrin SR

 

Wellbutrin

 

Zoloft

 

Paxil

 

Effexor XR

 

Effexor

 

Serzone

 

Luvox

 

Remeron

 

 

 

 

 

Nardil

 

Parnate

Daily Dosage (mg)


150-300

 

150-300

 

150-300

 

75-125

 

15-40

 

100-300

 

150-300

 

150-225

 

150-400

 

150-400

 

20-80

 

150-300

 

150-400

 

50-200

 

20-50

 

75-300

 

75-375

 

100-500

 

50-300

 

15-45

 

 

 

 

 

30-90

 

20-60

 

Sedation

 

mid

 

low

 

high

 

mid

 

mid

 

high

 

high

 

high

 

mid

 

mid

 

low

 

low

 

low

 

low

 

low

 

low

 

low

 

mid

 

low

 

mid

 

 

 

 

 

Low

 

Low

 

Weight Gain

 

mid

 

low

 

high

 

low

 

low

 

high

 

high

 

mid

 

low

 

low

 

none

 

none

 

none

 

none

 

none

 

none

 

none

 

none

 

none

 

high

 

 

 

 

 

mid

 

low

 

Information from Consumers Guide to Psychiatric Drugs
2001
 

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